It is strongly encouraged to organize your work within a self-contained R project. An R project is a way to store all files related to one project in one place (R scripts, source files, location of the R working directory, RStudio workspace).
Read more about a project-oriented workflow in this tidyverse article: https://www.tidyverse.org/articles/2017/12/workflow-vs-script/
Select File -> New Project from the top RStudio menu.
Creating a new R project will create:
Navigate and open project files, such as scripts, using the Files tab of the lower-right RStudio pane.
For an RMarkdown to produce the final report correctly, you must have read/write permissions for the location of the R project folder. On an MSF computer this is generally the c:/temp folder.
One significant benefit of working within an R project is that all associated files (datasets, etc.) are located within the same folder. Thus, to send the project to someone else, simply zip the folder and send. All files referenced in the scripts are included and no file pathways in the script are unique to your computer.